1 TITLE : Sec 15 is an Effector for the Rab 11 GTPase in Mammalian Cells
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چکیده
منابع مشابه
TBC domain family, member 15 is a novel mammalian Rab GTPase-activating protein with substrate preference for Rab7.
Ypt/Rabs are Ras-related GTPases that function as key regulators of intracellular vesicular trafficking. Their slow intrinsic rates of GTP hydrolysis are catalyzed by GTPase-activating proteins (GAPs). Ypt/Rab-GAPs constitute a family of proteins that contain a TBC (Tre-2/Bub2/Cdc16) domain. Only three of the 51 family members predicted in the human genome are confirmed Ypt/Rab-GAPs. Here, we r...
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